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The Work We Fund

Funded projects

1,250+

Men's Health Partners

Countries

We work closely with our global men's health partners to ensure collaboration, transparency and accountability for every project we fund. We monitor this through report cards which detail what we seek to achieve, key measures and the impact.

Prostate Cancer

"Together with the brightest minds in research, we aim to achieve significant breakthroughs in the hope of beating prostate cancer. Our disruptive funding approach identifies revolutionary ways to accelerate health outcomes by creating strong, global collaborative teams." Dr. Colleen Nelson, Global Scientific Chair.

Men's Health

"One Mo can help change the face of men’s health through the powerful conversations created globally during Movember. Men have the chance to confidently discuss men’s health with people around them, resulting in men taking action early, helping change and save lives." Paul Villanti, Executive Director, Programs

Mental health and suicide prevention

“The number of men taking their own lives around the world is one of the biggest challenges of our time. Movember is working to ensure all men and boys look after their mental health and are comfortable to seek help when they’re struggling.”
Brendan Maher, Global Director, Mental Health and Suicide Prevention.

Testicular Cancer

“Despite being the 2nd most common cancer in young men, testicular cancer is often a forgotten cancer due to early detection and treatment. Our projects look at underinvested areas such as improving access to healthcare services and treatment options for relapse” Paul Villanti, Executive Director, Programs.

Quantitative Proteomic Profiling Facilitates Biomarker and drug target discovery in Prostate Cancer

Movember Funding to Date

DKK 2,500,000

What we seek to achieve

To improve the implementation of individualized treatments for men with prostate cancer through a better understanding of the protein alterations that occur in tumors.

Country: Denmark
Implemented by: Faculty of Health and Medical Sciences. University of Copenhagen
Project start date: December 2013
Project Status: Project Completed

About the project

Prostate tumors arise due to the accumulation of genetic alterations in prostate cells that result in uncontrolled cell proliferation, resulting in tumor growth. The mechanisms that translate genetic changes into altered cellular function necessarily involve changes in multiple proteins that facilitate tumor development. Indeed, proteins are the ultimate executors of cell functions and as such play an essential role in all the cellular processes that lead to cancer. Importantly, most drugs are directed towards proteins. Therefore, the implementation of individualized therapies for prostate cancer can be facilitated by a better understanding of the protein alterations that occur within tumors.

Our research team leveraged recent advances in mass spectrometry based protein analysis to implement novel methodologies that allow a comprehensive quantitative proteomic profiling of prostate cancer samples. This study will identify protein alterations that occur in tumors and determine how they relate to genetic changes and/or lead to disease severity, thereby facilitating the identification of proteins more likely to be useful as biomarkers or targets for pharmaceutical intervention against prostate cancer.

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Prostate Cancer Research Alliance

The Program will fund research that leverages Australia's existing strengths in prostate cancer biomedical research to deliver outcomes that can be translated into clinical practice within the next 5 to 7 years.

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